Functional materials, V.7, No.1

Studies of phospholipid membranes. 2. Protolytic behaviour of hydrophobic indicator dyes in mixed phosphatidylcholine-diphosphatidylglycerol liposomes and in micelles of surfactants

N.O.Mchedlov-Petrossyan, G.P.Gorbenko, N.A.Vodolazkaya, V.I.Alekseeva^*, L.P.Savvina^*

V.Karazin Kharkiv National University, 4 Svobody Sq., Kharkiv 61077, Ukraine ^*Research Institute of Organic Intermediates and Dyes, Moscow 103787, Russia

Received August 29, 1999

The "apparent" pK_a^a values of two indicator dyes, decylfluorescein and 2,6-diphenyl-4-(2,4,6-triphenyl-1-pyridinio) phenoxide, are determined spectrophotometrically in the suspension of liposomes composed of phosphatidylcholine and diphosphatidylglycerol (18:1, mol:mol), as well as in micellar solutions of nonyl phenol 12, Tween 80 and sodium dodecyl sulfate. The pK_a^a values of dyes, bound by liposomes, are intermediate between those in the case of micelles of non-ionic and anionic surfactants.

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